Weight Loss
Retatrutide, 5-Amino-1MQ and other compounds discussed for weight loss: what they are and what the research shows.
5-Amino-1MQ: the 'fat-loss peptide' that is actually a small molecule
5-Amino-1MQ is sold and discussed as a fat-loss peptide, but it is a small molecule that blocks the enzyme NNMT. What it is, what it does, what the cell and mouse studies show, what is unknown about side effects, how it compares with MOTS-c and retatrutide, and what is known about stacking it.
Retatrutide: what it is, what the trials actually measured, and when it might be available
A plain-spoken overview of retatrutide, Eli Lilly's investigational GIP, GLP-1 and glucagon triple agonist: how it works, what the phase 2 and phase 3 trials measured, its side effects, how it compares with Ozempic and Zepbound, what it costs, why it dominates weight-loss threads online, and what is known about timing.